Blar i forfatter "Latini, Roberto"

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    • Circulating levels and prognostic cut-offs of sST2, hs-cTnT, and NT-proBNP in women vs. men with chronic heart failure 

      Vergaro, Giuseppe; Gentile, Francesco; Aimo, Alberto; Januzzi, James L.; Richards, A. Mark; Lam, Carolyn S.P.; de Boer, Rudolf A.; Meems, Laura M.G.; Latini, Roberto; Staszewsky, Lidia; Anand, Inder S.; Cohn, Jay N.; Ueland, Thor; Gullestad, Lars; Aukrust, Pål; Brunner-La Rocca, Hans-Peter; Bayes-Genis, Antoni; Lupón, Josep; Yoshihisa, Akiomi; Takeishi, Yasuchika; Egstrup, Michael; Gustafsson, Ida; Gaggin, Hanna K.; Eggers, Kai M.; Huber, Kurt; Gamble, Greg D.; Ling, Lieng H.; Leong, Kui Toh Gerard; Yeo, Poh Shuah Daniel; Ong, Hean Yee; Jaufeerally, Fazlur; Ng, Tze P.; Troughton, Richard; Doughty, Robert N.; Devlin, Gerry; Lund, Mayanna; Giannoni, Alberto; Passino, Claudio; Emdin, Michele (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-05)
      Aims To define plasma concentrations, determinants, and optimal prognostic cut-offs of soluble suppression of tumorigenesis-2 (sST2), high-sensitivity cardiac troponin T (hs-cTnT), and N-terminal pro-B-type natriuretic peptide (NTproBNP) in women and men with chronic heart failure (HF).<p> <p>Methods and results Individual data of patients from the Biomarkers In Heart Failure Outpatient Study ...

    • Circulating levels and prognostic value of soluble ST2 in heart failure are less influenced by age than N-terminal pro-B-type natriuretic peptide and high-sensitivity troponin T 

      Aimo, Alberto; Januzzi, James L.; Vergaro, Giuseppe; Richards, A. Mark; Lam, Carolyn S.P.; Latini, Roberto; Anand, Inder S.; Cohn, Jay N.; Ueland, Thor; Gullestad, Lars; Aukrust, Pål; Brunner-La Rocca, Hans-Peter; Bayes-Genis, Antoni; Lupón, Josep; de Boer, Rudolf A.; Takeishi, Yasuchika; Egstrup, Michael; Gustafsson, Ida; Gaggin, Hanna K.; Eggers, Kai M.; Huber, Kurt; Gamble, Greg D.; Ling, Lieng H.; Leong, Kui Tong Gerard; Yeo, Poh Shuah Daniel; Ong, Hean Yee; Jaufeerally, Fazlur; Ng, Tze P.; Troughton, Richard; Doughty, Robert N.; Passino, Claudio; Emdin, Michele (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-09)
      <i>Aims</i> - N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP), high‐sensitivity troponin T (hs‐TnT) and soluble suppression of tumorigenesis‐2 (sST2) predict outcome in chronic heart failure (HF). We assessed the influence of age on circulating levels and prognostic significance of these biomarkers.<p> <p><i>Methods and results</i> - Individual data from 5301 patients with chronic HF and ...

    • Re-appraisal of the obesity paradox in heart failure: a meta-analysis of individual data 

      Marcks, Nick; Aimo, Alberto; Januzzi, James L.; Vergaro, Giuseppe; Clerico, Aldo; Latini, Roberto; Meessen, Jennifer; Anand, Inder S.; Cohn, Jay N.; Gravning, Jørgen; Ueland, Thor; Bayes-Genis, Antoni; Lupón, Josep; de Boer, Rudolf A.; Yoshihisa, Akiomi; Takeishi, Yasuchika; Egstrup, Michael; Gustafsson, Ida; Gaggin, Hanna K.; Eggers, Kai M.; Huber, Kurt; Tentzeris, Ioannis; Ripoli, Andrea; Passino, Claudio; Sanders-van Wijk, Sandra; Emdin, Michele; Brunner-La Rocca, Hans-Peter (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-11)
      Background - Higher body mass index (BMI) is associated with better outcome compared with normal weight in patients with HF and other chronic diseases. It remains uncertain whether the apparent protective role of obesity relates to the absence of comorbidities. Therefore, we investigated the effect of BMI on outcome in younger patients without co-morbidities as compared to older patients with ...

    • Revisiting the obesity paradox in heart failure: Per cent body fat as predictor of biomarkers and outcome 

      Aimo, Alberto; Januzzi, James L.; Vergaro, Giuseppe; Clerico, Aldo; Latini, Roberto; Meessen, Jennifer; Anand, Inder S.; Cohn, Jay N.; Gravning, Jørgen A.; Ueland, Thor; Nymo, Ståle Haugset; Brunner-La Rocca, Hans-Peter; Bayes-Genis, Antoni; Lupón, Josep; de Boer, Rudolf A.; Yoshihisa, Akiomi; Takeishi, Yasuchika; Egstrup, Michael; Gustafsson, Ida; Gaggin, Hanna K.; Eggers, Kai M.; Huber, Kurt; Tentzeris, Ioannis; Ripoli, Andrea; Passino, Claudio; Emdin, Michele (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-01)
      <i>Aims</i> - Obesity defined by body mass index (BMI) is characterized by better prognosis and lower plasma N-terminal pro-B-type natriuretic peptide (NT-proBNP) in heart failure. We assessed whether another anthropometric measure, per cent body fat (PBF), reveals different associations with outcome and heart failure biomarkers (NT-proBNP, high-sensitivity troponin T (hs-TnT), soluble suppression ...

    • Secreted frizzled related protein 3 in chronic heart failure: Analysis from the controlled rosuvastatin multinational trial in heart failure (CORONA) 

      Askevold, Erik Tandberg; Gullestad, Lars; Nymo, Ståle Haugset; Kjekshus, John; Yndestad, Arne; Latini, Roberto; Cleland, John G.F.; McMurray, John J.V.; Aukrust, Pål; Ueland, Thor (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-19)
      Background We have previously demonstrated an association between increased sFRP3 expression and adverse outcome in a population of HF irrespective of cause and left ventricular ejection fraction. In this study we evaluated the prognostic value of sFRP3 in older patients with chronic systolic HF of ischemic origin. <p>Methods We evaluated sFRP3, by tertiles, as a risk factor for the primary ...